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Article

Low copy number of the FCGR3B gene and rheumatoid arthritis: a case-control study and meta-analysis.

Arthritis research & therapy - 7 Feb 2012

Graf Scott W, Lester Sue, Nossent Johannes C, Hill Catherine L, Proudman Susanna M, Lee Anita, Rischmueller Maureen

Abstract excerpt

INTRODUCTION: Low copy number (CN) of the Fc gamma receptor 3B (FCGR3B) gene has been associated with systemic autoimmune disease. This receptor for IgG is present almost exclusively on neutrophils and plays a role in their interaction with immune complexes. At present the relationship between FCGR3B and rheumatoid arthritis (RA) is unclear. The aim of the present study was to investigate whether low CN of the...

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Identifiers

PMID: 22309893
DOI: 10.1186/ar3731
PMCID: PMC3392823

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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