Article
Effect of multiple activation stimuli on the generation of Th1-polarizing dendritic cells.
Human immunology - 1 Jan 2011
Paustian Christopher, Caspell Richard, Johnson Terrence, Cohen Peter A, Shu Suyu, Xu Shuwen, Czerniecki Brian J, Koski Gary K
Abstract excerpt
It was originally reported that only a small fraction of total matured dendritic cells (DCs) produced interleukin (IL)-12, but it has never been determined whether different combinations of activating signals now shown to maximize secreted IL-12 do so through increasing output by the same IL-12 producers, or by recruiting additional cytokine-secreting cells. We therefore tested all combinations of bacterial...
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