IL-12 increases CD80 expression and the stimulatory capacity of bone marrow-derived dendritic cells.

doi:10.1093/intimm/10.6.749

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Article

IL-12 increases CD80 expression and the stimulatory capacity of bone marrow-derived dendritic cells.

International immunology - 1 Jun 1998

Kelleher P, Knight S C

Abstract excerpt

Dendritic cells (DC) are potent antigen-presenting cells derived from CD34 bone marrow stem cells. They undergo a series of maturational steps that allow them to stimulate primary T cell responses. Several cytokines are known to contribute to this process. In this study murine DC maturing from bo...

Topics

Age Factors
Animals
B7-1 Antigen
Bone Marrow
Dendritic Cells
Enzyme-Linked Immunosorbent Assay
Female
Flow Cytometry
Interleukin-12
Mice
Mice, Inbred BALB C
Phenotype
Time Factors

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