Article
Budding yeast Mph1 promotes sister chromatid interactions by a mechanism involving strand invasion.
DNA repair - 2 Jan 2011
Ede Christopher, Rudolph Christian J, Lehmann Sabrina, Schürer K Anke, Kramer Wilfried
Abstract excerpt
Stalling of replication forks at lesions is a serious threat to genomic integrity and cell viability. Cells have developed a variety of pathways that allow continuation of synthesis, including translesion synthesis, postreplication repair and homologous recombination. We have devised a sensitive genetic system for detection of sister chromatid interactions in Saccharomyces cerevisiae. A 266bp sequence duplication...
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