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Article

Mutational dynamics of murine angiogenin duplicates.

BMC evolutionary biology - 15 Oct 2010

Codoñer Francisco M, Alfonso-Loeches Silvia, Fares Mario A

Abstract excerpt

BACKGROUND: Angiogenin (Ang) is a protein involved in angiogenesis by inducing the formation of blood vessels. The biomedical importance of this protein has come from findings linking mutations in Ang to cancer progression and neurodegenerative diseases. These findings highlight the evolutionary constrain on Ang amino acid sequence. However, previous studies comparing human Angiogenin with homologs from other...

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Identifiers

PMID: 20950426
DOI: 10.1186/1471-2148-10-310
PMCID: PMC2964713

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