Article
Pseudogenization of the tumor-growth promoter angiogenin in a leaf-eating monkey.
Gene - 10 Apr 2003
Zhang Jianzhi, Zhang Ya-ping
Abstract excerpt
Physiological functions of human genes may be studied by gene-knockout experiments in model organisms such as the mouse. This strategy relies on the existence of one-to-one gene orthology between the human and mouse. When lineage-specific gene duplication occurs and paralogous genes share a certain degree of functional redundancy, knockout mice may not provide accurate functional information on human genes....
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