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Expansion and collapse of VEGF diversity in major clades of the animal kingdom

5 Apr 2023

Abstract excerpt

Together with the platelet-derived growth factors (PDGFs), the vascular endothelial growth factors (VEGFs) form the PDGF/VEGF subgroup among cystine knot growth factors. The evolutionary relationships within this subgroup have not been examined thoroughly to date. Here, we comprehensively analyze the PDGF/VEGF growth factors throughout all animal phyla and propose a phylogenetic tree. Vertebrate whole-genome...

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PMID: 37017884
DOI: 10.1007/s10456-023-09874-9

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