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Molecular characterization of matrix metalloproteinase gene family across primates

20 Apr 2022

Abstract excerpt

Deregulation of matrix metalloproteinases (MMPs) contributes considerably to cancers, psychiatric disorders, macular degeneration and bone diseases. The use of humans in the development of MMPs as prognostic biomarkers and therapeutic targets is complicated by many factors, while primate models can be useful alternatives for this purpose. Here, we performed genome-enabled identification of putative MMPs across...

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PMID: 35444067
DOI: 10.18632/aging.204021

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