Adaptive functional divergence among triplicated alpha-globin genes in rodents.

doi:10.1534/genetics.107.080903

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Article

Adaptive functional divergence among triplicated alpha-globin genes in rodents.

Genetics - 1 Mar 2008

Storz Jay F, Hoffmann Federico G, Opazo Juan C, Moriyama Hideaki

Abstract excerpt

The functional divergence of duplicated genes is thought to play an important role in the evolution of new developmental and physiological pathways, but the role of positive selection in driving this process remains controversial. The objective of this study was to test whether amino acid differences among triplicated alpha-globin paralogs of the Norway rat (Rattus norvegicus) and the deer mouse (Peromyscus...

Topics

Amino Acid Sequence
Animals
Chromosomes, Artificial, Bacterial
Chromosomes, Mammalian
Gene Conversion
Genes, Duplicate
Genetic Variation
Genome
Globins
Guinea Pigs
Hemoglobins
Hydrogen Bonding
Likelihood Functions
Mice
Molecular Sequence Data

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Identifiers

PMID: 18245844
DOI: 10.1534/genetics.107.080903
PMCID: PMC2278084

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