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Article

Significance levels in genome-wide interaction analysis (GWIA).

Annals of human genetics - 1 Jan 2011

Becker Tim, Herold Christine, Meesters Christian, Mattheisen Manuel, Baur Max P

Abstract excerpt

Interaction between genetic variants is hypothesized to be one of several putative explanations for the 'case of missing heritability.' Therefore, Genome-Wide Interaction Analysis (GWIA) has recently gained substantial interest. GWIA is computationally challenging and respective power type I error studies are particularly difficult. Therefore, an accepted significance level for GWIA studies does not currently...

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PMID: 20950400
DOI: 10.1111/j.1469-1809.2010.00610.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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