Article

Neuropilin 1 (NRP1) conveys SEMA3A signals to restrict physiological angiogenesis

2025-05-28

Abstract excerpt

<title>Abstract</title> <p>The class 3 semaphorin SEMA3A is a secreted glycoprotein that serves as an evolutionary conserved axon repellent with proposed vascular functions. In mice, SEMA3A promotes vascular permeability in adults, but is dispensable for developmental brain, limb or trunk blood vessel patterning. By contrast, Sema3a restricts vessel branching in zebrafish embryo trunks. Whereas neuropilin 1 (NRP1...

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Literature Corpus work: c942d880-f366-58d9-ae98-6a848b3e07d6
DOI: 10.21203/rs.3.rs-6584058/v1

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