Article
Leptin increases motility and integrin up-regulation in human prostate cancer cells.
Journal of cellular physiology - 1 May 2011
Huang Chih-Yang, Yu Hsin-Shan, Lai Tung-Yuan, Yeh Yu-Lan, Su Cheng-Chuan, Hsu His-Hsien, Tsai Fuu-Jen, Tsai Chang-Hai, Wu Hsi-Chin, Tang Chih-Hsin
Abstract excerpt
Prostate cancer is the most commonly diagnosed malignancy in men and shows a predilection for metastasis to distant organs. Leptin, an adipocyte-derived cytokine that is closely associated with obesity, has recently been shown to be involved in carcinogenesis and cancer progression. The aim of th...
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