Article
Molecular interactions of leptin and prostate cancer.
Cancer journal (Sudbury, Mass.) - 1 Jan 2000
Gade-Andavolu Radhika, Cone Lawrence A, Shu Shinger, Morrow Ariela, Kowshik Beena, Andavolu Murthy V S
Abstract excerpt
BACKGROUND: Epidemiological studies have found obesity to be a risk factor for prostate cancer. Our prior independent studies in women have reported a strong relationship between variants of OB (leptin) gene, body mass index, and age at menarche and sporadic breast cancer. The current study investigates an association between genetic variants of the human obesity gene, serum leptin levels, and body mass index in...
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