Article
Prostate cancer cell proliferation and angiogenesis in different obese mice models.
International journal of experimental pathology - 1 Aug 2010
Ribeiro Andreia M, Andrade Sara, Pinho Filipa, Monteiro J Duarte, Costa Madalena, Lopes Carlos, Aguas Artur P, Monteiro Mariana P
Abstract excerpt
Obesity has been associated with increased incidence and aggressiveness of prostate cancer. Although controversial, several studies suggest that leptin could influence tumour cell growth and proliferation. The main goal of this study was to assess cellular growth of prostate adenocarcinoma cells in obese mice with different endogenous hormonal environments in what relates to leptin circulating levels and...
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