Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Leptin signalling, obesity and prostate cancer: molecular and clinical perspective on the old dilemma.

Oncotarget - 3 Nov 2015

Alshaker Heba, Sacco Keith, Alfraidi Albandri, Muhammad Aun, Winkler Mathias, Pchejetski Dmitri

Abstract excerpt

The prevalence of global obesity is increasing. Obesity is associated with general cancer-related morbidity and mortality and is a known risk factor for development of specific cancers. A recent large systematic review of 24 studies based on meta-analysis of 11,149 patients with prostate cancer showed a significant correlation between obesity and the risk of advanced prostate cancer. Further, a sustained...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue
Share to Carcinogenesis
Share to Janus Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leptin

Share to Obesity

Share to Prostatic Neoplasms

Share to Receptors, Leptin

Share to STAT3 Transcription Factor

Source

Open in PubMed Open full text

Identifiers

PMID: 26376613
DOI: 10.18632/oncotarget.5574
PMCID: PMC4742124

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Leptin signalling, obesity and prostate cancer: molecular and clinical perspective on the old dilemma.PMID 26376613Read ↗

Leptin and prostate: implications for cancer prevention--overview of genetics and molecular interactions.Semantic proximity Read ↗

Metabolic Syndrome and Prostate Cancer: a Review of Complex Interplay Amongst Various Endocrine Factors in the Pathophysiology and Progression of Prostate Cancer.Semantic proximity Read ↗

Decoding the Influence of Obesity on Prostate Cancer and Its Transgenerational ImpactSemantic proximity Read ↗

Genetic polymorphisms in leptin, adiponectin and their receptors affect risk and aggressiveness of prostate cancer: evidence from a meta-analysis and pooled-review.Semantic proximity Read ↗

Molecular interactions of leptin and prostate cancer.Semantic proximity Read ↗

The pleiotropic roles of leptin in metabolism, immunity, and cancer.Semantic proximity Read ↗

Leptin Signaling in Obesity and Colorectal CancerSemantic proximity Read ↗

The intricate role of adipokines in cancer-related signaling and the tumor microenvironment: Insights for future researchSemantic proximity Read ↗

Alteration of Lipid Metabolism in Prostate Cancer: Multifaceted Oncologic ImplicationsSemantic proximity Read ↗

Obesity and Breast Cancer: Molecular Interconnections and Potential Clinical ApplicationsSemantic proximity Read ↗

Obesity and Prostate Cancer: A Focused Update on Active Surveillance, Race, and Molecular Subtyping.Semantic proximity Read ↗

Obesity and cancer—extracellular matrix, angiogenesis, and adrenergic signaling as unusual suspects linking the two diseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.