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Article

Leptin requires canonical migratory signaling pathways for induction of monocyte and macrophage chemotaxis.

American journal of physiology. Cell physiology - 1 Nov 2007

Gruen Marnie L, Hao Mingming, Piston David W, Hasty Alyssa H

Abstract excerpt

The growing worldwide obesity epidemic is frequently linked to an increased risk of developing diseases such as diabetes, cardiovascular disease, and cancer. These diseases are associated with the infiltration of macrophages in white adipose tissue (WAT), the artery wall, and tumors, respectively; and these macrophages likely contribute to disease progression and pathogenesis. Abdominal WAT, adipose tissue...

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Identifiers

PMID: 17728393
DOI: 10.1152/ajpcell.00062.2007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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