Article
Control of lung development by latent TGF-β binding proteins.
Journal of cellular physiology - 1 Jun 2011
Dabovic Branka, Chen Yan, Choi Jiwon, Davis Elaine C, Sakai Lynn Y, Todorovic Vesna, Vassallo Melinda, Zilberberg Lior, Singh Amanjot, Rifkin Daniel B
Abstract excerpt
The latent TGF-β binding proteins (LTBP-1 -3, and -4) assist in the secretion and localization of latent TGF-β molecules. Ltbp3(-/-) and Ltbp4S(-/-) mice have distinct phenotypes and only in the lungs does deficiency of either Ltbp-3 or Ltbp-4 cause developmental abnormalities. To determine if th...
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