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Article

Dual functions for LTBP in lung development: LTBP-4 independently modulates elastogenesis and TGF-beta activity.

Journal of cellular physiology - 1 Apr 2009

Dabovic Branka, Chen Yan, Choi Jiwon, Vassallo Melinda, Dietz Harry C, Ramirez Francesco, von Melchner Harald, Davis Elaine C, Rifkin Daniel B

Abstract excerpt

The latent TGF-beta binding proteins (LTBP) -1, -3, and -4 are extracellular proteins that assist in the secretion and localization of latent TGF-beta. The null mutation of LTBP-4S in mice causes defects in the differentiation of terminal air-sacs, fragmented elastin, and colon carcinomas. We inv...

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Source

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Identifiers

PMID: 19016471
DOI: 10.1002/jcp.21643
PMCID: PMC2719250

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19016471-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Dual functions for LTBP in lung development: LTBP-4 independently modulates elastogenesis and TGF-beta activity.PMID 19016471Read ↗

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