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Article

The mitochondrial bioenergetic phenotype for protection from cardiac ischemia in SUR2 mutant mice.

American journal of physiology. Heart and circulatory physiology - 1 Dec 2010

Aggarwal Nitin T, Pravdic Danijel, McNally Elizabeth M, Bosnjak Zeljko J, Shi Nian-Qing, Makielski Jonathan C

Abstract excerpt

The sulfonylurea receptor-2 (SUR2) is a subunit of ATP-sensitive potassium channels (K(ATP)) in heart. Mice with the SUR2 gene disrupted (SUR2m) are constitutively protected from ischemia-reperfusion (I/R) cardiac injury. This was surprising because K(ATP), either sarcolemmal or mitochondrial or...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mitochondria, Heart

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Share to Sulfonylurea Receptors

Source

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Identifiers

PMID: 20935152
DOI: 10.1152/ajpheart.00363.2010
PMCID: PMC3006279

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20935152-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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