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Article

Linkage to the 8p21.1 region Including the CLU gene in age at onset stratified alzheimer's disease families.

Journal of Alzheimer's disease : JAD - 1 Jan 2011

Sillén Anna, Lilius Lena, Forsell Charlotte, Kimura Toru, Winblad Bengt, Graff Caroline

Abstract excerpt

Two powerful genome-wide association studies have recently reported significant association between sporadic late-onset Alzheimer's disease (AD) and markers at the CLU locus in chromosome 8p. In this study, we have stratified our previously analyzed 109 Swedish AD families according to range in age at onset and performed whole-genome linkage analysis and subsequent fine-mapping in 8p21. The subgroup analyzed in...

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Source

Identifiers

PMID: 20930273
DOI: 10.3233/JAD-2010-101359

Genes

CLU
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Linkage to the 8p21.1 region Including the CLU gene in age at onset stratified alzheimer's disease families.PMID 20930273Read ↗

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