Article
Linkage and association study of late-onset Alzheimer disease families linked to 9p21.3.
Annals of human genetics - 1 Nov 2008
Züchner S, Gilbert J R, Martin E R, Leon-Guerrero C R, Xu P-T, Browning C, Bronson P G, Whitehead P, Schmechel D E, Haines J L, Pericak-Vance M A
Abstract excerpt
A chromosomal locus for late-onset Alzheimer disease (LOAD) has previously been mapped to 9p21.3. The most significant results were reported in a sample of autopsy-confirmed families. Linkage to this locus has been independently confirmed in AD families from a consanguineous Israeli-Arab community. In the present study we analyzed an expanded clinical sample of 674 late-onset AD families, independently...
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