Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Haptoglobin genotype modifies the association between dietary vitamin C and serum ascorbic acid deficiency.

The American journal of clinical nutrition - 1 Dec 2010

Cahill Leah E, El-Sohemy Ahmed

Abstract excerpt

BACKGROUND: Haptoglobin (which is encoded by the Hp gene) is a hemoglobin-binding protein that has antioxidant properties and a common polymorphism that consists of 2 structurally different alleles: Hp1 and Hp2. The capacity of Hp2 to inhibit oxidation and vitamin C depletion is less than that of Hp1, but the influence on vitamin C requirements remains unknown. OBJECTIVE: This study aimed to determine whether the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Ascorbic Acid
Share to Diet

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Haptoglobins

Share to Odds Ratio

Share to Polymorphism, Genetic

Share to Surveys and Questionnaires

Share to Young Adult

Source

Identifiers

PMID: 20926521
DOI: 10.3945/ajcn.2010.29306

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Haptoglobin genotype modifies the association between dietary vitamin C and serum ascorbic acid deficiency.PMID 20926521Read ↗

Vitamin C deficiency and scurvy are not only a dietary problem but are codetermined by the haptoglobin polymorphism.Semantic proximity Read ↗

Human genetic variation influences vitamin C homeostasis by altering vitamin C transport and antioxidant enzyme function.Semantic proximity Read ↗

Lack of association between oxidized LDL-cholesterol concentrations and haptoglobin phenotypes in healthy subjects.Semantic proximity Read ↗

Functional genetic variants of glutathione S-transferase protect against serum ascorbic acid deficiency.Semantic proximity Read ↗

The protean role of haptoglobin and haptoglobin genotypes on vascular complications in diabetes mellitus.Semantic proximity Read ↗

Haptoglobin: basic and clinical aspects.Semantic proximity Read ↗

Haptoglobin genotype is a consistent marker of coronary heart disease risk among individuals with elevated glycosylated hemoglobin.Semantic proximity Read ↗

Genetic polymorphisms as determinants for disease-preventive effects of vitamin ESemantic proximity Read ↗

Role of Haptoglobin 2-2 genotype on disease progression and mortality among South Indian Chronic Kidney Disease PatientsSemantic proximity Read ↗

Vitamin C transporter gene polymorphisms, dietary vitamin C and serum ascorbic acid.Semantic proximity Read ↗

Polymorphism of human haptoglobin and its clinical importanceSemantic proximity Read ↗

Role of haptoglobin 2-2 genotype on disease progression and mortality among South Indian chronic kidney disease patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.