Article
Haptoglobin: basic and clinical aspects.
Antioxidants & redox signaling - 1 Feb 2010
Levy Andrew P, Asleh Rabea, Blum Shany, Levy Nina S, Miller-Lotan Rachel, Kalet-Litman Shiri, Anbinder Yefim, Lache Orit, Nakhoul Farid M, Asaf Roy, Farbstein Dan, Pollak Mordechai, Soloveichik Yitzhak Z, Strauss Merav, Alshiek Jonia, Livshits Alina, Schwartz Avery, Awad Hoda, Jad Kheir, Goldenstein Hagit
Abstract excerpt
Haptoglobin is an abundant hemoglobin-binding protein present in the plasma. The function of haptoglobin is primarily to determine the fate of hemoglobin released from red blood cells after either intravascular or extravascular hemolysis. There are two common alleles at the Hp genetic locus denoted 1 and 2. There are functional differences between the Hp 1 and Hp 2 protein products in protecting against...
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