Article
Polymorphism of human haptoglobin and its clinical importance
2008-01-01
Abstract excerpt
Haptoglobin (Hp) is a plasma glycoprotein, the main biological function of which is to bind free hemoglobin (Hb) and prevent the loss of iron and subsequent kidney damage following intravascular hemolysis. Haptoglobin is also a positive acute-phase protein with immunomodulatory properties. In humans, the HP locus is polymorphic, with two codominant alleles (HP1 and HP2) that yield three distinct genotypes/phenotyp...
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Identifiers and source
- Literature Corpus work
- b12b763d-b672-5939-a206-82d72ab6db3d
- DOI
- 10.1590/s1415-47572008000400002