Article
Functional genetic variants of glutathione S-transferase protect against serum ascorbic acid deficiency.
The American journal of clinical nutrition - 1 Nov 2009
Cahill Leah E, Fontaine-Bisson Bénédicte, El-Sohemy Ahmed
Abstract excerpt
BACKGROUND: Glutathione S-transferases (GSTs) are detoxifying enzymes that contribute to the glutathione-ascorbic acid (vitamin C) antioxidant cycle. OBJECTIVE: The objective was to determine whether GST genotypes modify the association between dietary vitamin C and serum ascorbic acid. DESIGN: Nonsmoking men and women (n = 905) between 20 and 29 y of age were participants in the Toronto Nutrigenomics and Health...
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