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Article

Effects of curvature and composition on α-synuclein binding to lipid vesicles.

Biophysical journal - 6 Oct 2010

Middleton Elizabeth R, Rhoades Elizabeth

Abstract excerpt

Parkinson's disease is characterized by the presence of intracellular aggregates composed primarily of the neuronal protein α-synuclein (αS). Interactions between αS and various cellular membranes are thought to be important to its native function as well as relevant to its role in disease. We use fluorescence correlation spectroscopy to investigate binding of αS to lipid vesicles as a function of the lipid...

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Identifiers

PMID: 20923663
DOI: 10.1016/j.bpj.2010.07.056
PMCID: PMC3042580

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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