Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic and epigenetic characteristics of human multiple hepatocellular carcinoma.

BMC cancer - 6 Oct 2010

Taniguchi Kazuya, Yamada Terumasa, Sasaki Yo, Kato Kikuya

Abstract excerpt

BACKGROUND: Multiple carcinogenesis is one of the major characteristics of human hepatocellular carcinoma (HCC). The history of multiple tumors, that is, whether they derive from a common precancerous or cancerous ancestor or individually from hepatocytes, is a major clinical issue. Multiple HCC is clinically classified as either intratumor metastasis (IM) or multicentric carcinogenesis (MC). Molecular markers...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Hepatocellular
Share to Chromosome Aberrations
Share to Comparative Genomic Hybridization

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Epigenesis, Genetic

Share to Epigenomics

Share to Genes, Tumor Suppressor

Share to Liver Neoplasms

Share to Neoplasm Metastasis

Source

Open in PubMed Open full text

Identifiers

PMID: 20923573
DOI: 10.1186/1471-2407-10-530
PMCID: PMC2978203

Genes

CTNNB1
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic and epigenetic characteristics of human multiple hepatocellular carcinoma.PMID 20923573Read ↗

Variable Intra-Tumor Genomic Heterogeneity of Multiple Lesions in Patients With Hepatocellular Carcinoma.Semantic proximity Read ↗

Distinction of intrahepatic metastasis from multicentric carcinogenesis in multifocal hepatocellular carcinoma using molecular alterations.Semantic proximity Read ↗

Genetic and Epigenetic Heterogeneity in Normal Liver Homeostasis and Its Implications for Liver Disease and Hepatocellular Cancer.Semantic proximity Read ↗

The genetic and epigenetic alterations in human hepatocellular carcinoma: a recent update.Semantic proximity Read ↗

Diverse modes of genomic alteration in hepatocellular carcinoma.Semantic proximity Read ↗

Multi-omics Analysis of Primary Cell Culture Models Reveals Genetic and Epigenetic Basis of Intratumoral Phenotypic Diversity.Semantic proximity Read ↗

Interplay of Genetic and Epigenetic Alterations in Hepatocellular CarcinomaSemantic proximity Read ↗

Inferring the progression of multifocal liver cancer from spatial and temporal genomic heterogeneity.Semantic proximity Read ↗

Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators.Semantic proximity Read ↗

Recent advancements in comprehensive genetic analyses for human hepatocellular carcinoma.Semantic proximity Read ↗

Overview and clinical significance of multiple mutations in individual genes in hepatocellular carcinomaSemantic proximity Read ↗

Integrative analysis of DNA methylation and gene expression reveals hepatocellular carcinoma-specific diagnostic biomarkersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.