Article
Recent advancements in comprehensive genetic analyses for human hepatocellular carcinoma.
Oncology - 1 Jan 2013
Nishida Naoshi, Kudo Masatoshi
Abstract excerpt
Hepatocellular carcinoma (HCC) typically develops in the liver with chronic hepatitis and cirrhosis, and activation of oncogenes and inactivation of tumor suppressor genes occurs during carcinogenesis via genetic and epigenetic mechanisms. Recent advancements in the development of analyses for ex...
Topics
- Carcinoma, Hepatocellular
- Evolution, Molecular
- Exome
- Genome-Wide Association Study
- Hepatitis B virus
- Humans
- Liver Neoplasms
- Polymorphism, Single Nucleotide
- Sequence Analysis, DNA