Article

Overview and clinical significance of multiple mutations in individual genes in hepatocellular carcinoma

2022-03-08

Abstract excerpt

Multiple mutation (MM) within a single gene has recently been reported as a mechanism involved in carcinogenesis. The present study investigated the clinical significance of MMs in hepatocellular carcinoma (HCC). Two hundred twenty-three surgically resected HCCs were subjected to gene expression profiling and whole-exome sequencing. MMs in individual genes were detected in 178 samples (MM tumors: 79.8%). The remai...

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Literature Corpus work: 53c42aa9-7e2a-5d44-9150-0fec2f413e27
DOI: 10.21203/rs.3.rs-676748/v2

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