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Article

Functional polymorphisms associated with disease-free survival in resected carcinoma of the esophagus.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract - 1 Jan 2011

Boonstra Jurjen J, van Marion Ronald, Tilanus Hugo W, Dinjens Winand N M

Abstract excerpt

PURPOSE: The aim of this study was to determine whether clinical outcome after surgical resection of esophageal adenocarcinoma (EAC) or esophageal squamous cell carcinoma (ESCC) could be predicted by functional polymorphisms in different proto-oncogenes and tumor suppressor genes. EXPERIMENTAL DESIGN: Six single nucleotide polymorphisms (SNPs) in the AURKA (rs2273535), ERBB2 (rs1136201), MDM2 (rs2279744), CDH1...

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Topics

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Share to Adenocarcinoma
Share to Carcinoma, Squamous Cell
Share to Disease-Free Survival
Share to DNA, Neoplasm
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Share to Genes, Tumor Suppressor
Share to Neoplasm Staging
Share to Proto-Oncogenes

Source

Open in PubMed Open full text

Identifiers

PMID: 20922573
DOI: 10.1007/s11605-010-1358-9
PMCID: PMC3023032

Genes

CDH1
MDM2
AHR
AURKA
ERBB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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