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Article

The survival impact of XPA and XPC genetic polymorphisms on patients with esophageal squamous cell carcinoma.

Annals of surgical oncology - 1 Feb 2013

Yang Pei-Wen, Hsieh Ching-Yueh, Kuo Fang-Tzu, Huang Pei-Ming, Hsu Hsao-Hsun, Kuo Shuenn-Wen, Chen Jin-Shing, Lee Jang-Ming

Abstract excerpt

BACKGROUND: The purpose of this study was to investigate the association between survival outcome of esophageal cancer patients and the genetic variants in xeroderma pigmentosum groups A (XPA) and C (XPC), 2 important molecules in the nucleotide excision pathway for DNA repair. METHODS: A total of 501 patients with a diagnosis of esophageal squamous cell carcinoma (ESCC) were enrolled in the study. The genetic...

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Identifiers

PMID: 22941172
DOI: 10.1245/s10434-012-2622-x

Genes

XPA
XPC

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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