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Article

KIF3A, a cilia structural gene on chromosome 5q31, and its polymorphisms show an association with aspirin hypersensitivity in asthma.

Journal of clinical immunology - 1 Feb 2011

Kim Jeong-Hyun, Cha Ji-Yeon, Cheong Hyun Sub, Park Jong Sook, Jang An Soo, Uh Soo-Taek, Kim Mi-Kyeong, Choi Inseon S, Cho Sang Heon, Park Byung-Lae, Bae Joon Seol, Park Choon-Sik, Shin Hyoung Doo

Abstract excerpt

INTRODUCTION: The kinesin family number 3A (KIF3A) gene on the human chromosomal 5q31-33 region, which is known as a susceptibility locus for immune diseases including asthma, plays a crucial role in generation of cilia. RESULTS: A treatment with aspirin in the human bronchial epithelial cells increased the mRNA expression level of KIF3A compared to that of the untreated control (P ≤ 0.01), and nasal polyp...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 20922562
DOI: 10.1007/s10875-010-9462-x

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FEV

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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