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Article

UBE3C genetic variations as potent markers of nasal polyps in Korean asthma patients.

Journal of human genetics - 1 Nov 2011

Pasaje Charisse Flerida A, Kim Jeong-Hyun, Park Byung-Lae, Park Jong-Sook, Uh Soo-Taek, Kim Mi-Kyeong, Park Choon-Sik, Shin Hyoung Doo

Abstract excerpt

The human ubiquitin protein ligase E3C (UBE3C) regulates airway inflammatory responses and is hypothesized to be associated with the presence of nasal polyps in asthma-related diseases. A total of 24 UBE3C single-nucleotide polymorphisms (SNPs) were genotyped in a 467 Korean asthma cohort that was stratified into more homogenous phenotypes of 114 aspirin-exacerbated respiratory disease subgroup and 353...

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Identifiers

PMID: 21881582
DOI: 10.1038/jhg.2011.104

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