Article
Functional variability of the adenosine A3 receptor (ADORA3) gene polymorphism in aspirin-induced urticaria.
The British journal of dermatology - 1 Nov 2010
Kim S-H, Nam E-J, Kim Y-K, Ye Y-M, Park H-S
Abstract excerpt
BACKGROUND: To improve understanding of aspirin hypersensitivity, this study focused on adenosine as a noncyclooxygenase target molecule of aspirin. Adenosine may affect the release of histamine from cutaneous mast cells through a mechanism mediated by the adenosine A3 receptor. OBJECTIVES: To investigate the genetic contribution of adenosine A3 receptor gene (ADORA3) polymorphisms in the pathogenesis of...
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