Article
Signaling mechanisms of cytokine receptors and their perturbances in disease.
Molecular and cellular endocrinology - 25 Feb 2000
Touw I P, De Koning J P, Ward A C, Hermans M H
Abstract excerpt
Cytokines regulate the proliferation and differentiation of cells through their interaction with specific receptors on the surface of target cells which are coupled to intracellular signal transduction pathways. The cytokine receptor class I superfamily, characterized by structural homology in the extracellular domain, includes receptors for many interleukins and hematopoietic growth factors, but also those of...
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