Article
The role of interleukin-1 in wound biology. Part I: Murine in silico and in vitro experimental analysis.
Anesthesia and analgesia - 1 Dec 2010
Hu Yajing, Liang Deyong, Li Xiangqi, Liu Hong-Hsing, Zhang Xun, Zheng Ming, Dill David, Shi Xiaoyou, Qiao Yanli, Yeomans David, Carvalho Brendan, Angst Martin S, Clark J David, Peltz Gary
Abstract excerpt
BACKGROUND: Wound healing is a multistep, complex process that involves the coordinated action of multiple cell types. Conflicting results have been obtained when conventional methods have been used to study wound biology. Therefore, we analyzed the wound response in a mouse genetic model. METHODS: We analyzed inflammatory mediators produced within incisional wounds induced in 16 inbred mouse strains....
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