Article
Association study by genetic clustering detects multiple inflammatory response loci in non-inbred mice.
Genes and immunity - 1 Jul 2011
Galvan A, Vorraro F, Cabrera W, Ribeiro O G, Starobinas N, Jensen J R, dos Santos Carneiro P, De Franco M, Gao X, Ibañez O C M, Dragani T A
Abstract excerpt
We tested the possibility to map loci affecting the acute inflammatory response (AIR) in an (AIRmax × AIRmin) F2 intercross mouse population derived from non-inbred parents, by association analysis in the absence of pedigree information. Using 1064 autosomal single nucleotide polymorphisms (SNPs), we clustered the intercross population into 12 groups of genetically related individuals. Association analysis...
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