Article
New quantitative trait loci that regulate wound healing in an intercross progeny from DBA/1J and 129 x 1/SvJ inbred strains of mice.
Functional & integrative genomics - 1 Apr 2006
Masinde Godfred L, Li Runzhi, Nguyen Bay, Yu Hongrun, Srivastava Apurva K, Edderkaoui Bouchra, Wergedal Jon E, Baylink David J, Mohan Subburaman
Abstract excerpt
Wound healing/regeneration mouse models are few, and studies performed have mainly utilized crosses between MRL/MPJ (a good healer) and SJL/J (a poor healer) or MRL/lpr (a good healer) and C57BL/6J (a poor healer). Wound healing is a complex trait with many genes involved in the expression of the phenotype. Based on data from previous studies that common and additional quantitative trait loci (QTL) were...
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