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Article

Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms.

Diabetes care - 1 Jan 2011

de Miguel-Yanes Jose M, Shrader Peter, Pencina Michael J, Fox Caroline S, Manning Alisa K, Grant Richard W, Dupuis Josèe, Florez Jose C, D'Agostino Ralph B, Cupples L Adrienne, Meigs James B

Abstract excerpt

OBJECTIVE: To test if knowledge of type 2 diabetes genetic variants improves disease prediction. RESEARCH DESIGN AND METHODS: We tested 40 single nucleotide polymorphisms (SNPs) associated with diabetes in 3,471 Framingham Offspring Study subjects followed over 34 years using pooled logistic regression models stratified by age (<50 years, diabetes cases = 144; or ≥50 years, diabetes cases = 302). Models included...

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Share to Diabetes, Cardiovascular Risks, and Lipoproteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genetic Predisposition to Disease

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Share to Pancreatic function and diabetes

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Identifiers

PMID: 20889853
DOI: 10.2337/dc10-1265
PMCID: PMC3005447

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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