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Article

Genotype score in addition to common risk factors for prediction of type 2 diabetes.

The New England journal of medicine - 20 Nov 2008

Meigs James B, Shrader Peter, Sullivan Lisa M, McAteer Jarred B, Fox Caroline S, Dupuis Josée, Manning Alisa K, Florez Jose C, Wilson Peter W F, D'Agostino Ralph B, Cupples L Adrienne

Abstract excerpt

BACKGROUND: Multiple genetic loci have been convincingly associated with the risk of type 2 diabetes mellitus. We tested the hypothesis that knowledge of these loci allows better prediction of risk than knowledge of common phenotypic risk factors alone. METHODS: We genotyped single-nucleotide polymorphisms (SNPs) at 18 loci associated with diabetes in 2377 participants of the Framingham Offspring Study. We...

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Share to Diabetes Mellitus, Type 2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genetic Predisposition to Disease

Share to Genotype

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 19020323
DOI: 10.1056/NEJMoa0804742
PMCID: PMC2746946

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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