Article
Use of multiple metabolic and genetic markers to improve the prediction of type 2 diabetes: the EPIC-Potsdam Study.
Diabetes care - 1 Nov 2009
Schulze Matthias B, Weikert Cornelia, Pischon Tobias, Bergmann Manuela M, Al-Hasani Hadi, Schleicher Erwin, Fritsche Andreas, Häring Hans-Ulrich, Boeing Heiner, Joost Hans-Georg
Abstract excerpt
OBJECTIVE: We investigated whether metabolic biomarkers and single nucleotide polymorphisms (SNPs) improve diabetes prediction beyond age, anthropometry, and lifestyle risk factors. RESEARCH DESIGN AND METHODS: A case-cohort study within a prospective study was designed. We randomly selected a subcohort (n = 2,500) from 26,444 participants, of whom 1,962 were diabetes free at baseline. Of the 801 incident type 2...
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