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Cell proliferation of human bone marrow mesenchymal stem cells on biodegradable microcarriers enhancesin vitrodifferentiation potential

30 Aug 2010

Abstract excerpt

OBJECTIVES: For reasons of provision of highly-specific surface area and three-dimensional culture, microcarrier culture (MC) has garnered great interest for its potential to expand anchorage-dependent stem cells. This study utilizes MC for in vitro expansion of human bone marrow mesenchymal stem cells (BMMSCs) and analyses its effects on BMMSC proliferation and differentiation. MATERIALS AND METHODS: Effects of...

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PMID: 20887551
DOI: 10.1111/j.1365-2184.2010.00694.x

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