Article
[Development of pulmonary chlamydia infection in inbred mice lines differentiated by genetically determinated sensitivity to tuberculosis infection].
Molekuliarnaia genetika, mikrobiologiia i virusologiia - 1 Jan 2010
Nesterenko L N, Aliapkina Iu S, Pashko Iu P, Kondrat'eva E V, Kapina M A, Balunets D V, Zagangirova N A, Romanova Iu M, Apt A S
Abstract excerpt
Mice of I/St strain develop severe lung inflammation and die shortly following infection with virulent mycobacteria. The susceptibility does not depend on the Nramp1 gene, as I/St mice carry its resistant allele, but is controlled by little interacting QTL mapped to chromosomes 3, 9, 17. To find out whether the tuberculosis-susceptible I/St mice are susceptible to other intracellular bacteria taxonomically...
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