Article
MicroRNAs Modulate Pathogenesis Resulting from Chlamydial Infection in Mice.
Infection and immunity - 1 Jan 2017
Yeruva Laxmi, Pouncey Dakota L, Eledge Michael R, Bhattacharya Sudeepa, Luo Chunqiao, Weatherford Erin W, Ojcius David M, Rank Roger G
Abstract excerpt
Not all women infected with chlamydiae develop upper genital tract disease, but the reason(s) for this remains undefined. Host genetics and hormonal changes associated with the menstrual cycle are possible explanations for variable infection outcomes. It is also possible that disease severity depends on the virulence of the chlamydial inoculum. It is likely that the inoculum contains multiple genetic variants,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.