Article
Differences in innate immune responses correlate with differences in murine susceptibility to Chlamydia muridarum pulmonary infection.
Immunology - 1 Apr 2010
Jiang Xiaozhou, Shen Caixia, Yu Hong, Karunakaran Karuna P, Brunham Robert C
Abstract excerpt
We investigated the phenotypic basis for genetically determined differences in susceptibility and resistance to Chlamydia muridarum pulmonary infection using BALB/c and C57BL/6 mice. Following C. muridarum intranasal inoculation, the intensity of infection was very different between BALB/c and C57BL/6 beginning as early as 3 days post-infection. Intrapulmonary cytokine patterns also differed at early time-points...
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