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Article

Phosphodiesterase 11A (PDE11A) genetic variants may increase susceptibility to prostatic cancer.

The Journal of clinical endocrinology and metabolism - 1 Jan 2011

Faucz Fabio Rueda, Horvath Anelia, Rothenbuhler Anya, Almeida Madson Q, Libé Rossella, Raffin-Sanson Marie-Laure, Bertherat Jerome, Carraro Dirce Maria, Soares Fernando Augusto, Molina Gustavo de Campos, Campos Antonio H, Alexandre Rodrigo B, Bendhack Marcelo Luiz, Nesterova Maria, Stratakis Constantine A

Abstract excerpt

CONTEXT: Among the genomic loci harboring potential candidate genes for prostatic cancer (PCa) is the 2q31-33 chromosomal region that harbors the gene encoding phosphodiesterase 11A (PDE11A). In addition, the combined cancer genome expression metaanalysis datasets included PDE11A among the top 1% down-regulated genes in PCa. OBJECTIVE: In the present study, we screened 50 unrelated PCa patients of Brazilian...

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Identifiers

PMID: 20881257
DOI: 10.1210/jc.2010-1655
PMCID: PMC3038491

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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