Article
Evaluation of PPP2R2A as a prostate cancer susceptibility gene: a comprehensive germline and somatic study.
Cancer genetics - 1 Jul 2011
Cheng Yu, Liu Wennuan, Kim Seong-Tae, Sun Jishan, Lu Lingyi, Sun Jielin, Zheng Siqun Lilly, Isaacs William B, Xu Jianfeng
Abstract excerpt
PPP2R2A, mapped to 8p21.2, codes for the α isoform of the regulatory B55 subfamily of protein phosphatase 2 (PP2A). PP2A is one of the four major serine/threonine phosphatases and is implicated in the negative control of cell growth and division. Because of its known functions and location within...
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