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Article

Evaluation of PPP2R2A as a prostate cancer susceptibility gene: a comprehensive germline and somatic study.

Cancer genetics - 1 Jul 2011

Cheng Yu, Liu Wennuan, Kim Seong-Tae, Sun Jishan, Lu Lingyi, Sun Jielin, Zheng Siqun Lilly, Isaacs William B, Xu Jianfeng

Abstract excerpt

PPP2R2A, mapped to 8p21.2, codes for the α isoform of the regulatory B55 subfamily of protein phosphatase 2 (PP2A). PP2A is one of the four major serine/threonine phosphatases and is implicated in the negative control of cell growth and division. Because of its known functions and location within a chromosomal region where evidence for linkage and somatic loss of heterozygosity was found, we hypothesized that...

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Identifiers

PMID: 21872824
DOI: 10.1016/j.cancergen.2011.05.002
PMCID: PMC3722858

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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