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Cyclooxygenase‐2 gene promoter polymorphisms affect susceptibility to hepatitis C virus infection and disease progression

28 Sept 2010

Abstract excerpt

AIM: Because polymorphisms of cyclooxygenase-2 (COX-2) and osteopontin (OPN) promoter regions and a promoter/enhancer region of forkhead box protein 3 (FOXP3) gene are known to affect immune responses, we examined whether these polymorphisms can influence susceptibility to hepatitis C virus (HCV) infection and progression of liver disease. METHODS: Peripheral blood samples were obtained from 104 Japanese patients...

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PMID: 20880066
DOI: 10.1111/j.1872-034x.2010.00727.x

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