Article
Polymorphisms of apolipoprotein E; outcome and susceptibility in multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Feb 2000
Weatherby S J, Mann C L, Davies M B, Carthy D, Fryer A A, Boggild M D, Young C, Strange R C, Ollier W, Hawkins C P
Abstract excerpt
Allelic variants of the apolipoprotein E (APOE) gene influence the course of several neurological diseases. In multiple sclerosis the concentration of APOE in cerebrospinal fluid and its intrathecal synthesis is reduced. Specific isoforms of APOE may also be important and it has been suggested th...
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