Article
The roles of stress-activated Sty1 and Gcn2 kinases and of the protooncoprotein homologue Int6/eIF3e in responses to endogenous oxidative stress during histidine starvation.
Journal of molecular biology - 26 Nov 2010
Nemoto Naoki, Udagawa Tsuyoshi, Ohira Takahiro, Jiang Li, Hirota Kouji, Wilkinson Caroline R M, Bähler Jürg, Jones Nic, Ohta Kunihiro, Wek Ronald C, Asano Katsura
Abstract excerpt
In fission yeast, Sty1 and Gcn2 are important protein kinases that regulate gene expression in response to amino acid starvation. The translation factor subunit Int6/eIF3e promotes Sty1-dependent response by increasing the abundance of Atf1, a transcription factor targeted by Sty1. While Gcn2 pro...
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